San Francisco, CA – Rescale, a digital engineering platform, has been awarded funding under the U.S. Department of Energy's (DOE) Genesis Mission for its Agentic HPC Pipeline Initiative (AHPI). The company was selected from a record-breaking field of over 8,000 applicants, joining national laboratories to apply agentic AI on national laboratory codes for U.S. industry. This initiative aims to significantly accelerate the adoption of advanced engineering simulation codes by American manufacturers.
The Genesis Mission, established by executive order in November 2025, is a national initiative led by the DOE to build the world’s most powerful integrated science discovery platform. It mobilizes 17 national laboratories and approximately 40,000 scientists and engineers to accelerate breakthroughs in energy, scientific discovery, and national security. The mission combines AI, supercomputing, quantum systems, and advanced scientific instruments, with an ambition comparable to the Manhattan Project and the Apollo program.
Rescale is the sole commercial technology company participating in the AHPI consortium, working alongside Lawrence Berkeley, Lawrence Livermore, and Oak Ridge National Laboratories. The project focuses on extending agentic AI capabilities into simulation codes like WarpX, LiDO, and Adamantine. This integration will guide engineers through code selection, input configuration, simulation monitoring, and results analysis.
The primary goal of the AHPI project is to reduce the engineering expertise and time required to run these complex simulations by more than fivefold. This will provide American manufacturers with self-service access to tools that have historically demanded direct laboratory support and specialized knowledge. The Genesis Mission’s first major funding opportunity, a $293 million round, supported national science and technology challenges across various sectors.
Joris Poort, CEO of Rescale, emphasized the importance of the collaboration, stating, > "The Genesis Mission recognizes that maximizing the return on both public and private investment in industrial AI technology depends on delivering these capabilities to the leading R&D teams who can put them to work." He added that Rescale's 15 years of experience positions them to bring advanced AI-driven simulation work into production use. Peter Nugent, Division Deputy for Science at Lawrence Berkeley National Laboratory, noted, > "Through AHPI, Berkeley Lab, together with Livermore and Oak Ridge, delivers those advances to the American manufacturers who can build on them."
This award builds on existing collaborations and aims to bridge the gap in lab-industry partnerships where tools often become inaccessible after project terms conclude. By keeping agentic workflows and configured code environments on the Rescale platform, AHPI ensures continuous collaboration and access for national laboratories and industry partners on critical technology challenges.
