Janus Henderson Integrates Ethena's USDe into Treasury, Invests in ENA, and Explores Crypto ETPs

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London, UK – Janus Henderson, a global asset manager overseeing approximately $480 billion in assets, has announced a multi-faceted strategic partnership with Ethena Labs, the developer of the synthetic dollar protocol USDe. The collaboration involves a strategic investment in Ethena's governance token, ENA, and the integration of USDe into Janus Henderson's treasury cash management strategy. This move signals a deeper engagement of traditional finance with decentralized finance (DeFi) infrastructure.

The asset manager's blockchain venture, ANTIK, made the strategic investment in the ENA token. Simultaneously, Janus Henderson plans to allocate a portion of its treasury cash into USDe, Ethena's yield-bearing synthetic dollar. This decision underscores a growing interest among institutional players in leveraging on-chain instruments for liquidity and treasury functions.

Further expanding the partnership, both firms are actively exploring the development of regulated investment products, including exchange-traded funds (ETFs) and exchange-traded products (ETPs), for both USDe and ENA. These products are targeted for launch in the second half of 2026, aiming to provide Janus Henderson clients with regulated exposure to the Ethena ecosystem. Nick Cherney, Head of Innovation at Janus Henderson Investors, expressed enthusiasm for the collaboration, stating, "We believe very deeply that innovation in blockchain is being led by the DeFi community."

As part of the agreement, Ethena will incorporate Janus Henderson’s JAAA strategy, which invests in AAA-rated collateralized loan obligations (CLOs), into USDe's reserve portfolio. This integration diversifies USDe's backing beyond crypto-native collateral and marks a significant step in blending real-world assets with DeFi. Ethena, which manages approximately $5 billion in assets, aims to expand its institutional reach through such partnerships, following recent collaborations with Coinbase Ventures and Anchorage Digital.